Eunice Kennedy Shriver National Institute Of Child Health And Human Development

Like PAIS, the choice of hormone treatments determines the physical gender of the adult with Partial Gonadal Dysgenesis. Lack of knowledge, awareness and psychosocial impact are all reasons Klinefelter’s syndrome is typically underdiagnosed. Men typically use health services less frequently than women.

How many people are affected by or at risk for Klinefelter syndrome ? Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. You may also look for a support group, where you can talk with others who have this condition. You can find support groups through your doctor or online.

In the pediatric years, the emphasis is on addressing learning and behavioral challenges and on identifying physical differences that may benefit from surgery or other intervention as needed. At Mass General, the brightest minds in medicine collaborate on behalf of our patients to bridge hookupgenius.com innovation science with state-of-the-art clinical medicine. Few men have ever heard of Klinefelter’s syndrome, and similarly would be unaware of the symptoms. For example, many men would not know what the typical size of the testes is, and so may be unaware they have small testes.

Famous People with Klinefelter Syndrome: Number 1 & 7 Is Shocking

Also, delays in motor development may occur, which can be addressed through occupational and physical therapies. XXY males may sit up, crawl, and walk later than other infants; they may also struggle in school, both academically and with sports. It is estimated that 10% of those with Klinefelter syndrome are autistic. Klinefelter syndrome is one of the most common chromosomal disorders, occurring in one to two per 1,000 live male births. It is named after American endocrinologist Harry Klinefelter, who identified the condition in the 1940s. In 1956, the extra X chromosome was identified as the cause.

Hard to de-tangle that, for sure, and especially since I don’t have some of the proto-typical KS symptoms. The side effects from the testosterone on his personality only aggravated his depression. I tried my very best for almost 20 years, but in the end he became violent and got fired from jobs. He refused therapy or to even consider he played a part in the problem. I am so very sorry you are in this situation, it really destroyed me. Hi, I hope by now you have gotten your husband in to see an endocrinologist to get his testosterone checked.

Klinefelter’s syndrome cases in the UK

We’ve had time to think on it and while we’ve decided not to go down either of those roads, it was good to know we had choices. I found out the hard way I had Klinefelter syndrome. When I married my wife, I didn’t have an overbearing desire to have children – I was just rapt to marry my best friend. I thought a family would come naturally down the track. You just assume it’s going to happen for you when you’re ready.

Gonadal Dysgenesis—One in 150,000 births

Most infertility blogs, FB sites, and support groups deal with the IVF cycle and other treatments. We had to face the fact that there was not even hope and almost no social support to lean on. We grieved the loss and by God’s grace have been able to embrace the amazing and beautifully untraditional life He has planned for us. Klinefelter syndrome is a common genetic condition where a male is born with an extra X chromosome.

Conditions & Treatments

No differences were seen between KS patients treated with testosterone and untreated KS patients. Check your sperm health with an at-home semen analysis kit and explore our guide to sperm improvement for more resources. In August 2022, a team of scientists published a study of a skeleton found at Torre Velha, Municipality of Bragança in north-eastern Portugal. The male was buried in a cut grave around 1,000CE, and found from DNA tests to be the earliest known person with this syndrome.

Others have problems early in life with delayed developmental milestones or with learning problems during their school years. Sometimes chromosomes join but do not form standard 46,XX or 46,XY combinations. Individuals with Klinefelter Syndrome are genetically 47,XXY and live as men. Small penis and testes, low androgen secretion, and possible female breast development are characteristics of this syndrome.

A “Y” chromosome indicates the presence of a male. Then, a year after my diagnosis, my sister Teresa was told she had cervical cancer. She died a year later, aged 30, before I had a chance to confide in her.

Klinefelter syndrome is one of the most popular chromosomal conditions affecting children, especially males. Approximately 1 in about 500 to 800 male children are born with this disorder yearly. One study found that Klinefelter Syndrome resulted in an average IQ score of 98 in boys, compared to 112 in other boys. Klinefelter Syndrome had a range of IQ values ranging from 70 to 130, indicating that in boys who have the condition, above-average intelligence is likely to be possible.

This 2013 study indicates that 70% of individuals with Klinefelter syndrome experience reduced libido and sexual function from the age of 25. Studies show that Klinefelter syndrome is found to be the cause of infertility in 10% of azoospermic males, and accounts for 2% of all cases of infertility. This type of azoospermia is known as “nonobstructive” — it’s not caused by a blockage in the vas deferens, ejaculatory duct, or epididymis.